Demcon kryoz
  • Full service
  • Expertise
    • Cryogenics
    • Cooling techniques
    • Vacuum techniques
    • Gasses and liquids
  • OEM products
    • cryocooling for high-res microscopy
    • Cooling for small satellites
  • About us
  • Showcases
  • Contact
  • career
  • news
Cryocooler product image banner v2
  1. Home›
  2. OEM products›
  3. Cryocooling for high-res microscopy

cryocooling for high-res microscopy

At Demcon kryoz we have developed an ultra-low- vibration miniature cryogenic cooler as a OEM-product. 

Combining ultra-stable performance, cryogen-free simplicity, and advanced movement control, this cryocooler sets a new standard for high-resolution microscopy. It’s more than a cooling system—it’s a precision platform that supports your next breakthrough.

highlights

• Turnkey solution
  Fully automated system with minimal installation demands.
• Vibrations levels < 1 nm p2p with < 3 nm/min drift
  Ultra-low vibration and thermal drift levels.
• Wide temperature range: 100 – 473 K ± 10 mK
  Variable temperature control across the entire range.
• Cryogen-free system
  No LN2, no cryogen handling, no frost, no hassle.
• Move your sample in six-degrees-of-freedom
  Cryocooler allows for movement in 6 DOF.

Cryogenic microcooler SON, SEM v4

ultra-low vibration
cryocooling.

The compact cryocooler delivers cooling down to 100 K while enabling full 360° movement and rotation, giving you unmatched flexibility for your experiments. It seamlessly integrates with your translation stage at room temperature, providing precise, automated temperature control from elevated to cryogenic levels with exceptional stability. Choose from a range of optimized cold head layouts, each designed to maximize performance for your specific application.

full Motion Freedom and Easy Integration.

Unlike traditional cooling systems, this cryocooler allows full spatial control of your sample. Six degrees of freedom enable precise alignment with lenses, detectors, or beams, while the compact design fits standard translation stages using M3 screw connections. It integrates effortlessly into existing microscopy setups and is controlled via a user-friendly module or remotely through USB—minimizing setup time and maximizing flexibility.

Cryogenic sample holder on B-DOF stage

sample Handling and Vacuum Compatibility.

Sample exchange is quick and flexible. The cryocooler supports both standard and custom holders and is designed to operate in high-vacuum environments (10⁻⁴ mbar or better), often supplied by the microscope. Custom vacuum chambers and interfaces from Demcon Kryoz ensure optimized performance for your application.

Cryogenic sample holder

stable, Cryogen-Free Cooling with Minimal Vibration.

This fully cryogen-free system delivers highly stable cooling from 100 K to 473 K with ±10 mK accuracy—no liquid nitrogen, no gas handling, and no frost buildup. Its closed-loop design ensures reliable, maintenance-free operation, while ultra-low vibration levels (<1 nm peak-to-peak) and minimal drift (<3 nm/min) make it ideal for nanoscale imaging applications where thermal and mechanical stability are critical.

Temperature gradient oven microcooler

Extreme stable temperatur

Translation-stage interface is at room temperature.
Controllable sample temperature from 300 down to 100 Kelvin.
High temperature stability ±10 mK.
 

Vibration stability graph

Extreme stable position

Low vibration level ~ 1 nm p2p.
Low drift levels of <3 nm min-1.

Performance testing was done using a TF Helios FIB/SEM/FM with the cryocooler mounted on a 5 DOF manipulation stage.

Temperature stabilization graph

“our aim as OEM.”

Currently we are searching to extend the application of this OEM product to users within or outside the CryoEM application field.

Interested? Please contact us!

Contact-demcon-kryoz-pieter

Pieter Lerou

+31 (0)88 115 20 00
contact us
Demcon kryoz
ServicesProductsExpertisesAbout usShowcasesNewsCareer

contact us

Demcon kryoz
+31 88 115 20 00

Send A Message
Demcon kryoz is part of the Demcon group
Cookie policyPrivacy statement
© 2025 Demcon. All rights reserved.